ANTIOXIDANTS
The recommended daily dose contains 400 mg of reduced L-glutathione. Additional ingredients: purified water, vegetable glycerin, soy lecithin, polysorbate 80, lemon flavor, potassium sorbate, menthol flavor, sucralose.
Glutathione is a tripeptide consisting of three amino acids (glutamine, cysteine and glycine) (tri = three + peptide = low molecular weight protein). It is very widespread in the living world, it is found in the cells of all living organisms. Important sources of food are the liver, spleen, bone marrow and spinal cord, and blood (blood clot). Most of the natural glutathione is broken down during digestion and barely absorbed. Human glutathione is produced by the liver from its components. Cabbage, kale, Chinese cabbage, Brussels sprouts, broccoli, radishes, turnips, milk, whey and egg whites, as well as foods containing vitamins B6, B9, B12, C and E, biotin and selenium contain little glutathione. but they stimulate its production in the liver. Among our medicinal plants, milk thistle (Sylibum marianum) is also credited with its ability to increase glutathione production. The extraordinary ability of glutathione is that it can oxidize on its own, but also restore (reduce) oxidized compounds! The former is carried out as a raw material for an enzyme called glutathione peroxidase (GSSG), while the latter is converted into glutathione-S transferase (GST). Glutathione is converted into one form or another as needed. With this, we can say that he can control most of the detoxification processes by himself!Dr. According to Mark Hayman, an American researcher, glutathione is the master detoxifier, the "mother of all antioxidants" and the maestro of the immune system! The GSH / GSSG ratio in the blood plasma is a reliable marker of the body's the extent of detoxification processes: if the amount of GSSG increases, it means that the body is fighting intensively against poisons and free radicals. In such cases, the body is capable of fighting! If the amount of GSH is normal and the amount of GSSG is less, it indicates that the body is not overloaded with such harmful substances. After the GSSG has used the free radicals to protect the body, the GST destroys the radicals that still remain in excess, preventing them from causing damage to our own cells. The fight against free radicals is especially important in those organs that are in contact with the outside world (skin, intestinal wall, bronchi). and mucous membrane of air sacs), and in the liver, which is the largest chemical plant in our body. This defense system is the most extensive, it works in the space between cells and in each type of cell separately. In addition, glutathione can neutralize oxidoreduction chemical poisons and heavy metal salts that have entered the body. Moreover, it also protects the eyes from the harmful effects of UV radiation (UV radiation also produces harmful free radicals in the tissues of the fundus and skin!).
The liposome is practically a shell phospholipid (in this case soy lecithin) with a structure similar to a cell membrane, in which certain nutrients and active ingredients are "packaged". This coat provides some protection from the digestive enzymes and allows the toxin to pass through the intestinal wall and cell membranes in increased quantities. With this, the naturally poorly absorbed active ingredient can be delivered to the target cells in a biologically effective amount.
Due to its widespread and multifaceted effects, it is difficult to link the free radical antioxidant system to specific organ effects. Because it protects all kinds of cells, tissues and organs chemically, it watches over the well-being of all cells and the health of the whole body. It is useful for general health protection and for slowing down aging. Recognition of the biological effect of glutathione began with the observation of its reduced presence in aging and chronically ill organisms. Men and women over the age of 60, whose body had more glutathione than the average for their age group, were in all cases in better physical, mental and spiritual condition than their contemporaries. In chronic respiratory diseases: Scientific studies have found a clear connection with chronic respiratory diseases such as pulmonary asthma, chronic obstructive respiratory failure (COPD), acute respiratory distress syndrome (ARDS), pulmonary fibrosis, and even disorders caused by immature respiratory development in premature babies. In addition to glutathione deficiency, the frequency of lung adenocarcinoma (a type of lung cancer) was found to be significantly higher. The drug N-acetylcysteine, used in obstructive respiratory diseases, also works by stimulating glutathione. In digestive diseases. The intestinal tract is also our largest immune organ: here we come into contact with the "dirty" outside world on the largest surface, and about 70% of our immune cells work here. Glutathione deficiency is associated with inflammatory processes in the digestive system. In Crohn's disease, glutathione deficiency can only be detected specifically limited to the diseased section of the intestine. Helicobacter pylori infections are also often associated with low glutathione content. In both acute and chronic liver inflammation, a decrease in glutathione levels was found in blood serum, red blood cells and immune cells. In liver cirrhosis, especially in non-alcoholic liver cirrhosis, there is a particularly low level of GSH, with a very high amount of GSSG. To protect red blood cells, to reduce the risk of hemolytic anemia. In addition to cytochrome enzymes, red blood cells work with the most oxygen. Molecular oxygen is a vital substance, but at the same time, atomic oxygen (broken from a molecular bond or not yet in a molecular bond) is a strong cell poison. For this reason, the oxygen-carrying task of red blood cells is considered a very dangerous operation at the cellular level. Without the protection of the GSH – GSSG – GST system, the lifespan of red blood cells is significantly shortened, they die and fall apart more quickly and at a greater rate. This leads to hemolytic anemia (caused by the disintegration of red blood cells). In malignant diseases, it is widely believed that an essential difference between healthy and cancerous cells is oxygen consumption. Most cancer cells have an anaerobic (oxygen-free) metabolism. The enzyme glutathione peroxidase forces these cells to absorb oxygen, which is poison for them, but indifferent to healthy cells. In this way, it "forces" cancer cells to commit suicide. Laboratory research has yielded promising results in the case of several cancer cell lines, as well as studies conducted on a few experimental animals. Used alongside chemotherapy (cisplatin) in women with ovarian cancer, it reduced the unpleasant side effects of the treatment, while improving its effectiveness. Similar experiences have been reported in patients treated for stomach cancer. Significantly different results were found for oral glutathione supplementation between male and female patients with liver cancer: although the amount of glutathione in the blood serum did not increase, it had a positive effect on female patients, while it was mostly ineffective on males. In malnourished patients with colon and rectal tumors, however, oral administration has also proven to be effective. In degenerative nervous system diseases. Very low GSH levels have been found in many neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease. Below 70% of the normal level, increased destruction of nerve cells was observed. Glutathione given orally had a positive effect on the condition of some autistic patients, even if its amount did not increase in the blood serum. Low levels of glutathione were typically found in HIV-infected patients, in children and infants born with HIV infection, in their blood plasma, red blood cells and circulating immune cells (monocytes and T -lymphocytes). Glutathione supplementation applied in an aerosol has proven to be beneficial. In addition to the above, it can also be used in cardiovascular diseases, diabetes, chronic inflammatory processes, acute and chronic infections, male infertility, etc. the reduction of glutathione in the body is also accepted as a factor.
If a doctor or pharmacist does not recommend otherwise, take 1 x 5 ml per day (measuring cup included in the packaging), either alone or mixed in cold drinking water, tea, or fruit juice. It can be consumed at any time of the day, but preferably there should be a 24-hour interval between consumptions. Do not mix it into a hot drink, avoid caffeine and alcoholic or carbonated drinks. L-glutathione is a natural substance present in all living cells. Allergies or sensitivities are not known. It can be consumed safely as long as the regulations are followed. Do not exceed the recommended dose. The product contains soy lecithin and should be avoided if you have a soy allergy. A large overdose may cause crampy diarrhea. Alleviating such diarrhea is not advisable - the sooner the excess lecithin is eliminated, the sooner the complaints will disappear. This does not require medical care. Its use on children is unjustified and contraindicated. Due to the lack of information, it is not recommended for pregnant and lactating mothers. The dietary supplement does not replace a balanced diet and a healthy lifestyle. Packaging and storage of Antioxidants The liquid dietary supplement is sold in a dark-colored bottle with a safety ring cap. Filling volume 250 ml (40 servings). Dosing cup in the packaging. It can be stored in the original packaging, at room temperature, protected from sunlight and radiant heat, until the expiration date indicated on the packaging without deterioration. After opening, it is recommended to refrigerate and consume within 50 days at most. Keep out of the reach of children!Note: Glutathione is a sulfur-containing substance. A characteristic sulfur smell when opening the bottle is a natural phenomenon, it does not mean a deterioration in quality. This review was written and edited for general information purposes by Dr. Csaba Gothárd, physician, dietary supplement consultant. It does not serve to diagnose or treat diseases and does not replace medical care.